Medicine. In Barcelona, was the first transplant of trachea using the patient's own stem cells. All cells of the donor organ was removed and replaced with cells created in laboratory collected from the patient. Technique can be held in Portugal
The transplant pioneer of trachea with a patient's own stem cells, held in Spain, could be done in Portugal, as also have the technical means to intervene. But the president of the Portuguese Society of Transplantation (SPT), Anthony Morais Sarmento, warning that the high cost of the technology necessary "can not compensate when they are only two speeches a year."
The Colombian Claudia Castillo, 30 years, was submitted in June, an innovator of tracheal transplantation does not involve the use of drugs that prevent rejection of organs. A process which involved researchers Spanish, English and Italian. The trachea transplant was "manufactured" to the extent of the patient, using their own stem cells through which does not need immune-suppressing drugs, which can cause hypertension, renal failure and cancer.
Once you have found the donor of trachea, researchers at the University of Padua in Italy, withdrew it with all the cells, reducing it to a simple tube of fabric. Meanwhile, the University of Bristol, UK, a sample was collected from bone marrow of Claudia Castillo to convert stem cells into millions of cartilage and epithelial cells (cells that cover the bodies), which will take the removal of the donor trachea. To complete the construction of "new" trachea, the University of Milan, Italy, used a bio-reactor for putting new cells to be transplanted in the trachea. To complete the process, the team of thoracic surgery of the Hospital of the University of Barcelona (Spain), led by Paolo Macchiarini, made the speech.
The technology needed for surgery and the scarcity of cases in Portugal, makes this method is not to apply, for now, despite the success recognized. The transplant was only "a specific case and very high costs involved, for the work of teams from three countries," the Lusa said Dominic Henry, coordinator of the Office of Development Biology at the Institute of Molecular Medicine (IMM), Faculty of Medicine of the University of Lisbon. The experts stressed, however, that the technique "represents a part of the future of medicine."
Also the chairman of SPT believes that "the cost of creating this technology and teams that make these interventions, to make two surgeries a year, does not pay." But Anthony Morais Sarmento caveat that "the technique is very beautiful and it results in more people is possible that groups in Portugal which is enthusiasm and begin using this technique."
Four months after the transplant, doctors say Claudia Castillo can now take care of daughters, 15 and four years, climbing stairs and walking reasonable distances without having shortness of breath. The patient contracted a tuberculosis four years ago, it has serious injuries in trachea and breathing difficulties. Before leaving for the transplant, doctors have to consider taking the lung of Colombia.
The transplant pioneer of trachea with a patient's own stem cells, held in Spain, could be done in Portugal, as also have the technical means to intervene. But the president of the Portuguese Society of Transplantation (SPT), Anthony Morais Sarmento, warning that the high cost of the technology necessary "can not compensate when they are only two speeches a year."
The Colombian Claudia Castillo, 30 years, was submitted in June, an innovator of tracheal transplantation does not involve the use of drugs that prevent rejection of organs. A process which involved researchers Spanish, English and Italian. The trachea transplant was "manufactured" to the extent of the patient, using their own stem cells through which does not need immune-suppressing drugs, which can cause hypertension, renal failure and cancer.
Once you have found the donor of trachea, researchers at the University of Padua in Italy, withdrew it with all the cells, reducing it to a simple tube of fabric. Meanwhile, the University of Bristol, UK, a sample was collected from bone marrow of Claudia Castillo to convert stem cells into millions of cartilage and epithelial cells (cells that cover the bodies), which will take the removal of the donor trachea. To complete the construction of "new" trachea, the University of Milan, Italy, used a bio-reactor for putting new cells to be transplanted in the trachea. To complete the process, the team of thoracic surgery of the Hospital of the University of Barcelona (Spain), led by Paolo Macchiarini, made the speech.
The technology needed for surgery and the scarcity of cases in Portugal, makes this method is not to apply, for now, despite the success recognized. The transplant was only "a specific case and very high costs involved, for the work of teams from three countries," the Lusa said Dominic Henry, coordinator of the Office of Development Biology at the Institute of Molecular Medicine (IMM), Faculty of Medicine of the University of Lisbon. The experts stressed, however, that the technique "represents a part of the future of medicine."
Also the chairman of SPT believes that "the cost of creating this technology and teams that make these interventions, to make two surgeries a year, does not pay." But Anthony Morais Sarmento caveat that "the technique is very beautiful and it results in more people is possible that groups in Portugal which is enthusiasm and begin using this technique."
Four months after the transplant, doctors say Claudia Castillo can now take care of daughters, 15 and four years, climbing stairs and walking reasonable distances without having shortness of breath. The patient contracted a tuberculosis four years ago, it has serious injuries in trachea and breathing difficulties. Before leaving for the transplant, doctors have to consider taking the lung of Colombia.
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